![]() ![]() (Unfortunately, actual measurements were not available.) This osmotic shift would induce water-based cellular swelling, decreased ventricular volume ( 4), and decreased diffusivity ( 5) until counteracted by cell volume regulation mechanisms ( 6). ![]() For example, if glucose dropped from 300 mg/dL to 63 mg/dL within 1 h, similar to other large sudden glucose drops observed in his CGM data, then plasma osmolality is estimated to have dropped from 297 mOsmol/kg to 282 mOsmol/kg ( 3). We speculate that these characteristics were an osmotic response to a sudden large drop in blood glucose shortly before the time 1 scan. ![]() This case is notable for the unusually large gray matter volume and cortical thickness at time 1 relative to the other time points. The CGM data were not collected immediately before or during any MRI scan. Continuous glucose monitoring (CGM) data collected for a total of 39 days showed a mean glucose (± SD) level of 235 ± 88 mg/dL and numerous large, rapid changes in sensor glucose, with increases as large as 200 mg/dL and decreases as large as 334 mg/dL within 1 h. His medical history included one hypoglycemic event with disorientation at age 6.3 years (10 weeks before the first MRI scan) and one hospitalization for diabetic ketoacidosis at age 11.5 years (15 weeks before the third MRI scan). Moreover, he had age-appropriate vocabulary and stable cognitive test scores over the 5-year period. He was healthy besides type 1 diabetes, prepubertal, with full-term birth, normal weight development, normal thyroid function, and no evidence of neurological deficits. The patient was on multiple daily insulin injections at the time of his first MRI scan and on infusion pump therapy at the later scans. Neuroradiological reviews of the MRI scans at each time point reported no evidence of gross pathological abnormalities or diffusion restrictions. Select Custom Mosaic Tiles from Mosaic menu.The patient was diagnosed with type 1 diabetes at age 5.6 years when he presented without diabetic ketoacidosis. Mazaika Lite allows you insert your own image as a tile like a sort of signature or hidden picture riddle. To replace a tile image simply click on the tile with your right mouse button (or use Ctrl+ Click) and select a new image from popup menu. ![]() You may adjust how often every single image is repeated in mosaic, you may manually change and replace every tile in mosaic with a suitable candidate image from the library. To save mosaic press Export button, and select a needed output size.įor advanced users Mazaika Lite allows full control over mosaic creation. Mosaic can be saved as a jpeg image file. Resulted image changes will be visible in real time. Simply press Enhanced and adjust Blending and Correction levels. Mosaic can be enhanced with color corrections. main mosaic theme picture), or simply drop it into the program's screen from finder.ģ - Select how many rows and columns you want in your mosaic. You may use images from iPhoto or Aperture albums or images from folders on your hard disc.Ģ - Open source image (i.e. With Mazaika Lite you can fast and easy assemble a photo mosaic from your own images and save it into jpeg image file with longest side up to 4200 pixel.ġ - Create a library from your own images. From a distance this mosaic looks like one big image, but as you zoom in, it becomes clear that it's not just a single, large picture but rather a collection of small, separate images. Mazaika makes composite image from hundreds of smaller images. ![]()
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